What happens to the body to cause polydipsia,polyuria and polyphagia in a person with type 1 diabetes?
CHEZ asked:
what are the actions occurring in the body to develop these symptoms.
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February 9th, 2010 01:27
High amounts of glucose in the urine can cause increased urine output and lead to dehydration. Dehydration causes increased thirst and water consumption. polydipsia and polyuria
Insulin is an Anabolic hormone that causes the storage of protein and fats and when its deficient, eventually causes weight loss even with the increased appetite.polyphagia
February 9th, 2010 18:51
In a diabetes sufferer, polydipsia, polyuria, and polyphagia are all inter-related.
In a type 1 diabetic there is a lack of insulin, primarily because your body’s own autoimmune system has destroyed the beta cells (islets of Langerhans) in the pancreas that produce this hormone.
Insulin is required to ‘transport’ glucose, from the breakdown of carbohydrates and starches that you eat, to ‘feed’ the muscles. The muscles ‘burn’ glucose to make energy, and thus keep you alive.
Obviously, whilst this can’t take place, the glucose level in your bloodstream builds up. Your kidneys ‘work overtime’ attempting to get rid of this excess glucose, and excrete it via urine. (Polyuria)
Because you’re ****** so much, in an attempt to get rid of all this extra glucose, your kidneys absorb moisture from other bodily organs leading to thirst. (Polyuria)
The polyphagia comes about as the result of your body’s cells ’starving’ as they can’t utilise [utilize] the glucose that’s present. In an attempt to survive, your body goes into the ‘misguided belief’ that you are starving. Hence you want to eat more.
The symptoms also occur in type 2 diabetics, but the onset is usually much slower, and may not be so noticeable initially. This is one of the reasons that type 2s can go years before actually being diagnosed.